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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 857403Generated: October 30, 2026

Benzothiazole-2-carbonyl chloride → (+/-)-[9-(1,3-BENZOTHIAZOL-2-YLCARBONYL)-8-BROMO-6-FLUORO-2,3-DIHYDRO-1H-PYRROLO[1,2-a]INDOL-1-YL]ACETIC ACID

https://huagongshe.com/reaction/857403

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzothiazole-2-carbonyl chlorideHCID 2776254—
ReactantHCID 21867442HCID 21867442—
Product(+/-)-[9-(1,3-BENZOTHIAZOL-2-YLCARBONYL)-8-BROMO-6-FLUORO-2,3-DIHYDRO-1H-PYRROLO[1,2-a]INDOL-1-YL]ACETIC ACIDHCID 10116276—

Reaction Steps

Starting from (+/−)-methyl(8-bromo-6-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate (Example 7, Step 8) and 1,3-benzothiazole-2-carbonyl chloride, the title compound was synthesized following the procedures described in Step 1 of Example 61 and Step 10 of Example 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07144913B2
Source datasetuspto-grants-2006_12
ORD IDord-cb71c6d0cd454d7ca99d8d04b196f228
Source noteuspto-grants-2006_12