Bromine → HCID 12054423, compound

HRID 857404Notes

Reaction equation

HRID 857404 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:8]=[CH:7][C:6]([SH:9])=[CH:5][CH:4]=1.BrBr>CCOCC>[F:11][C:2]([F:1])([F:10])[C:3]1[CH:4]=[CH:5][C:6]([S:9][S:9][C:6]2[CH:7]=[CH:8][C:3]([C:2]([F:11])([F:10])[F:1])=[CH:4][CH:5]=2)=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 24408BromineHCID 1366534-(Trifluoromethyl)thiophenol

Product 1

HCID 12054423HCID 12054423, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 4-(trifluoromethyl)benzenethiol (1 g) in Et2O was added bromine until orange color remained. The addition was stopped and the organic layer was washed with 1:1 aqueous saturated NaHCO3/10% aqueous Na2S203, dried over Na2SO4 and concentrated to give the title compound used as such.

Workup

  1. additionThe addition
  2. washthe organic layer was washed with 1:1 aqueous saturated NaHCO3/10% aqueous Na2S203
  3. dry with materialdried over Na2SO4
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-2f295d233665407dbf094ffbea2d6caa
Source dataset
uspto-grants-2006_12
Patent number
US07144913B2

Reaction notes

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