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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 857405Generated: October 31, 2026

Quinaldoyl chloride → (+/-)-[8-BROMO-6-FLUORO-9-(QUINOLIN-2-YLCARBONYL)-2,3-DIHYDRO-1H-PYRROLO[1,2-a]INDOL-1-YL]ACETIC ACID

https://huagongshe.com/reaction/857405

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinaldoyl chlorideHCID 2760547—
ReactantHCID 21867442HCID 21867442—
Product(+/-)-[8-BROMO-6-FLUORO-9-(QUINOLIN-2-YLCARBONYL)-2,3-DIHYDRO-1H-PYRROLO[1,2-a]INDOL-1-YL]ACETIC ACIDHCID 58760727—

Reaction Steps

Starting from (+/−)-methyl(8-bromo-6-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate (Example 7, Step 8) and quinoline-2-carbonyl chloride, the title compound was synthesized following the procedures described in Step 1 of Example 61 and Step 10 of Example 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07144913B2
Source datasetuspto-grants-2006_12
ORD IDord-4d13d3293c9746d9bebf913578c45ed8
Source noteuspto-grants-2006_12