Hydrochloric Acid → HCID 69656116, compound

Participants

Reaction Steps

HCl gas was bubbled through a stirred 0° C. solution of 1-{(2R)-2-[(tert-butoxycarbonyl)amino]-2-cyclohexylethanoyl}-N-[5-chloro-2-(4-chloro-1,2,5-thiadiazol-3-yl)benzyl]-L-prolinamide (41.1 mg, 0.07 mmol) CH2Cl2 (1.0 mL) for 15 min. The solution was reduced in vacuo. 1-[(2R)-2-amino-2-cyclohexylethanoyl]-N-[5-chloro-2-(4-chloro-1,2,5-thiadiazol-3-yl)benzyl]-L-prolinamide hydrochloride was isolated as a solid. LCMS m/z=496.5.

Provenance & Evidence