Nickel(II) bromide → HCID 58761611, compound

HRID 857833Notes

Reaction equation

HRID 857833 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[N:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1.[Ni:23]([Br:25])[Br:24]>C1COCC1>[Ni:23]([Br:25])[Br:24].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[N:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1

Participants

4

Reactant 2

HCID 278492Nickel(II) bromideHCID 100629331-(pyridin-2-yl)-N-[(1R,2R)-2-{[(pyridin-2-yl)methylidene]amino}cyclohexyl]methanimine

Product 1

HCID 58761611HCID 58761611, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a baked Schlenk tube, 1.0 g (3.4 mmol) of trans-N,N′-bispyridin-2-ylmethylenecyclohexane-1,2-diamine are dissolved in 40 ml of THF and admixed with 1.04 g (3.4 mmol) of nickel(II) bromide*DME. After 0.2 h, the solution becomes dark. After stirring at room temperature for another 2 hours, the solvent is removed under reduced pressure and the residue is stirred with 10 ml of heptane. Filtration through a G3 frit gives the product as a dark blue solid in a yield of 1.32 g (2.58 mmol, 76%).

Workup

  1. customthe solvent is removed under reduced pressure
  2. stirringthe residue is stirred with 10 ml of heptane
  3. filtrationFiltration through a G3 frit

Sources & evidence

ORD record
ord-0dc707a4761c42d0a53a8f22063d6cf7
Source dataset
uspto-grants-2006_12
Patent number
US07148174B2

Reaction notes

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