Dichloromethane → 7-(piperidin-4-yloxy)-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one

HRID 85787Notes

Reaction equation

HRID 85787 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][n:17][c:18]3[n:19]4[c:24]([cH:25][c:26]3[cH:27]2)[C:23](=[O:28])[NH:22][CH2:21][CH2:20]4)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][n:17][c:18]3[n:19]4[c:24]([cH:25][c:26]3[cH:27]2)[C:23](=[O:28])[NH:22][CH2:21][CH2:20]4)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 684647274-(1-Oxo-1,2,3,4-tetrahydro-2,4a,5-triaza-fluoren-7-yloxy)-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 684660687-(piperidin-4-yloxy)-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one

Sources & evidence

ORD record
ord-08e7937ade7c4a9d9d3c8c08e2604c3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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