Hydrochloric Acid → 1-{2-[3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-8-phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl}-ethanone

HRID 85802Notes

Reaction equation

HRID 85802 reaction equation
[CH2:37]([Cl:38])[Cl:39].[CH3:2][O:3][c:4]1[cH:5][c:6]([NH:16][c:17]2[n:18][cH:19][c:20]3[c:21]([n:22]2)[CH:23]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:24][NH:25][CH2:26]3)[cH:7][cH:8][c:9]1-[n:10]1[cH:11][n:12][c:13]([CH3:15])[cH:14]1.[CH3:33][C:34]([Cl:35])=[O:36].[ClH:1]>>[CH3:2][O:3][c:4]1[cH:5][c:6]([NH:16][c:17]2[n:18][cH:19][c:20]3[c:21]([n:22]2)[CH:23]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:24][N:25]([C:34]([CH3:33])=[O:36])[CH2:26]3)[cH:7][cH:8][c:9]1-[n:10]1[cH:11][n:12][c:13]([CH3:15])[cH:14]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 44194158N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-8-phenyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Product 1

HCID 441941591-{2-[3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-8-phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl}-ethanone

Sources & evidence

ORD record
ord-ac0961bfcf144fbf90a070c924aa1907
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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