HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl triflate → 1-Methyl-1H-indole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl triflate | HCID 9526 | — |
| Reactant | 1H-Indole-5-Carboxylic Acid | HCID 74280 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Methyl-1H-indole-5-carboxylic acid | HCID 7015601 | — |
Reaction Steps
0.1 g of indol-5-carboxylic acid was mixed with 2 equivalents of methyl trifluoromethane sulfonate in 1 ml DMF at room temperature. After 5 h the solvent was evaporated and 1H-NMR was recorded:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07148243B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-a0d26f19bf7a4baf960f448a6e4bd646 |
| Source note | uspto-grants-2006_12 |