2,4-Dimethoxyaniline → 2-(3-Chloro-4-hydroxy-phenyl)-benzooxazol-6-ol

HRID 858219Notes

Reaction equation

HRID 858219 reaction equation
[CH3:1][O:2][C:3]1[CH:9]=[C:8]([O:10]C)[CH:7]=[CH:6][C:4]=1[NH2:5].[Cl:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22]C)C(O)=O>>[Cl:12][C:13]1[CH:14]=[C:15]([C:1]2[O:2][C:3]3[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:4]=3[N:5]=2)[CH:19]=[CH:20][C:21]=1[OH:22]

Participants

3

Reactant 2

HCID 176522,4-DimethoxyanilineHCID 1699823-Chloro-p-anisic acid

Product 1

HCID 1354961332-(3-Chloro-4-hydroxy-phenyl)-benzooxazol-6-ol

Procedure

The title compound was prepared in substantially the same manner as described in Example 1, from 2,4-dimethoxyaniline, and 3-chloro-4-methoxybenzoic acid and was obtained as an off-white solid, m.p. 254–256° C.; MS m/e 262 (M+H)+.

Workup

  1. customwas obtained as an off-white solid, m.p. 254–256° C.

Sources & evidence

ORD record
ord-65eb10d706414826ba3e340e370bc620
Source dataset
uspto-grants-2006_12
Patent number
US07148247B2

Reaction notes

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