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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858265Generated: October 30, 2026

4-Bromophenol → 1-Bromo-4-(methoxymethoxy)benzene

https://huagongshe.com/reaction/858265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromophenolHCID 7808—
ReactantChloromethyl Methyl EtherHCID 7864—
Product1-Bromo-4-(methoxymethoxy)benzeneHCID 10465919104.2%

Reaction Steps

In a manner similar to that of Example 7(a), by reaction of 48.84 g (282.3 mmol) of 4-bromophenol with 25.0 ml (310.5 mmol) of chloromethyl methyl ether, 63.85 g (100%) of the expected product are obtained in the form of a beige-coloured oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148245B2
Source datasetuspto-grants-2006_12
ORD IDord-4d470c1c4e2b45d9ac8c28245222b495
Source noteuspto-grants-2006_12