Dichloromethane → N-(4-methylsulfanyl-1-oxo-1-piperazin-1-ylbutan-2-yl)acetamide

HRID 85845Notes

Reaction equation

HRID 85845 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([C:14]([CH:15]([NH:16][C:17]([CH3:18])=[O:19])[CH2:20][CH2:21][S:22][CH3:23])=[O:24])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:32][CH2:33][Cl:34].[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[NH:8]1[CH2:9][CH2:10][N:11]([C:14]([CH:15]([NH:16][C:17]([CH3:18])=[O:19])[CH2:20][CH2:21][S:22][CH3:23])=[O:24])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22610742Tert-butyl 4-(2-acetamido-4-methylsulfanylbutanoyl)piperazine-1-carboxylate

Product 1

HCID 22610743N-(4-methylsulfanyl-1-oxo-1-piperazin-1-ylbutan-2-yl)acetamide

Sources & evidence

ORD record
ord-68503670fc8d4d2ca0cf148a7b951c72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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