HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 21876062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-amino-5,7-dimethyl-3-(4-{2-[({[(4-methylphenyl)sulfonyl]amino}carbonyl)amino]ethyl}phenyl)-3H-imidazo[4,5-b]pyridine | HCID 21875860 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 21876062 | HCID 21876062 | 5% |
Reaction Steps
2-amino-5,7-dimethyl-3-(4-{2-[({[(4-methylphenyl)sulfonyl]amino}carbonyl)amino]ethyl}phenyl)-3H-imidazo[4,5-b]pyridine (73 mg) was treated with pyridine (1 ml) and Ac2O (0.2 ml) at room temperature for 3 hours. After evaporation in vacuo, the residue was purified by preparative TLC (hexane/acetone=1/1) to afford 4 mg (5%) of the title compounds.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07148234B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-fdc420d50e054299af1a023a00786dec |
| Source note | uspto-grants-2006_12 |