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HRID858702

反应详情

EQUATION

反应方程式

HRID 858702 的结构方程式

REACTANTS

反应物

2
结构：N#CC1(c2ccc(Br)cc2F)CC1
HCID58762329

1-(4-Bromo-2-fluorophenyl)cyclopropane-1-carbonitrile

C10H7BrFN

结构：COc1cc(C(C)(C)C#N)c(F)cc1CCC1(C2CCCC2)CC(O)=CC(=O)O1
HCID68865262

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(C(C)(C)C#N)c(F)cc1Br
HCID68868796

4-Bromo-2-fluoro-5-methoxy-α,α-dimethylbenzeneacetonitrile

C11H11BrFNO

PROCEDURE

实验过程

The desired product was prepared analogously to Example A (97) step 2, substituting (4-Bromo-2-fluoro-5-methoxy-phenyl)-acetonitrile (1.95 g, 8.0 mmol) from step 4 below in place of 1-(4-bromo-2-fluoro-phenyl)-cyclopropanecarbonitrile. Yield: 8.72 g, 96.0%. 1H NMR (CDCl3) δ: 1.34 (s, 6H), 3.92 (s, 3H), 7.06 (d, J=6.8 Hz, 1H), 7.33 (d, J=10.6 Hz, 1H).