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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 85872Generated: October 25, 2026

Dichloromethane → 6-chloro-N-[3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl]-4-(trifluoromethyl)pyridine-3-carboxamide

https://huagongshe.com/reaction/85872

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant1-Amino-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]propan-2-olHCID 69627074—
Reactant4-Trifluoromethyl-6-chloronicotinoyl chlorideHCID 86611246—
Product6-chloro-N-[3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl]-4-(trifluoromethyl)pyridine-3-carboxamideHCID 90782865—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-9fd6167ceb56468e8d568a8d024d0d87
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)