Dichloromethane → 6-chloro-N-[3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl]-4-(trifluoromethyl)pyridine-3-carboxamide
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[Cl:47][CH2:48][Cl:49].[F:1][C:2]([c:3]1[cH:4][c:5]([Cl:12])[n:6][cH:7][c:8]1[C:9](=[O:10])[Cl:11])([F:13])[F:14].[NH2:15][CH2:16][CH:17]([CH2:18][N:19]1[CH2:20][CH2:21][CH:22]([O:25][c:26]2[cH:27][c:28]([Cl:33])[c:29]([Cl:32])[cH:30][cH:31]2)[CH2:23][CH2:24]1)[OH:34]>>[F:1][C:2]([c:3]1[cH:4][c:5]([Cl:12])[n:6][cH:7][c:8]1[C:9](=[O:10])[NH:15][CH2:16][CH:17]([CH2:18][N:19]1[CH2:20][CH2:21][CH:22]([O:25][c:26]2[cH:27][c:28]([Cl:33])[c:29]([Cl:32])[cH:30][cH:31]2)[CH2:23][CH2:24]1)[OH:34])([F:13])[F:14]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9fd6167ceb56468e8d568a8d024d0d87
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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