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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858744Generated: October 30, 2026

6-[2-(5-Chloro-2,4-dimethoxy-phenyl)ethyl]-6-cyclopentyl-tetrahydropyran-2,4-dione → HCID 136152588, compound

https://huagongshe.com/reaction/858744

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-[2-(5-Chloro-2,4-dimethoxy-phenyl)ethyl]-6-cyclopentyl-tetrahydropyran-2,4-dioneHCID 16728701—
Reactant2-(chloromethyl)-6,7-dimethoxyquinazolin-4(3H)-oneHCID 135473569—
ProductHCID 136152588HCID 13615258820%

Reaction Steps

The title compound was prepared as described in Example B(53), using 2-(chloromethyl)-6,7-dimethoxyquinazolin-4(3H)-one (Example B(57), Step 1) in place of 5-(chloromethyl)-1,3-dimethyl-1H-1,2,4-triazole, and using 6-[2-(5-chloro-2,4-dimethoxyphenyl)ethyl]-6-cyclopentyldihydro-2H-pyran-2,4(3H)-dione in place of 6-[2-(3-chloro-4-methoxyphenyl)ethyl]-6-cyclopentyldihydro-2H-pyran-2,4(3H)-dione. Yield: 20%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148226B2
Source datasetuspto-grants-2006_12
ORD IDord-f70a489fc3ed4e869fac1aab095dcf44
Source noteuspto-grants-2006_12