HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23063806, compound → 3-(5-Hydroxy-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23063806 | HCID 23063806 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(5-Hydroxy-1H-indol-3-yl)-1H-pyrrole-2,5-dione | HCID 21655843 | — |
Reaction Steps
3-(5-hydroxy-1H-indol-3-yl)-2,5-pyrrolidinedione 10% palladium-on-carbon (135 mg) is added to a solution of the compound of Step A of Preparation H (450 mg) in dry methanol (90 ml). After having purged in vacuo for 20 minutes, the reaction mixture is placed under a hydrogen atmosphere (1 atm) for 3 hours. Following filtration over Celite and evaporation of the filtrate, the expected product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07151108B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-5ed9bd6f1fc641e49664c5f0ba3e2c5a |
| Source note | uspto-grants-2006_12 |