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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 859508Generated: October 30, 2026

Trifluoroacetic acid → HCID 22224824, compound

https://huagongshe.com/reaction/859508

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86588010HCID 86588010—
SolventDichloromethaneHCID 6344—
ProductHCID 22224824HCID 22224824—

Reaction Steps

Prepared from {3-[3-(3-cyano-phenyl)-3-oxo-propionylamino]-3′-methoxy-biphenyl-4-yl}-carbamic acid tert.-butyl ester (Example K21) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a light yellow powder (118 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07151098B2
Source datasetuspto-grants-2006_12
ORD IDord-dcaa7768058447968563b9f4520571bb
Source noteuspto-grants-2006_12