HRID859563

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2F)cc1NC(=O)CC(=O)c1cc(C#N)ccc1F

HCID86588057

未命名化合物

PRODUCTS

生成物

结构：N#Cc1ccc(F)c(C2=Nc3ccc(-c4ccccc4F)cc3NC(=O)C2)c1

HCID22224952

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Prepared from {3-[3-(5-cyano-2-fluoro-phenyl)-3-oxo-propionylamino]-2′-fluoro-biphenyl-4-yl}-carbamic acid tert.-butyl ester (Example K72) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a yellow solid (92 mg).