HRID859567

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：Cc1cn(-c2nc(C(=O)CC(=O)Nc3cc(-c4ccc(F)cc4)ccc3NC(=O)OC(C)(C)C)cs2)cn1

HCID86588061

未命名化合物

PRODUCTS

生成物

结构：Cc1cn(-c2nc(C3=Nc4ccc(-c5ccc(F)cc5)cc4NC(=O)C3)cs2)cn1

HCID22224833

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Prepared from (4′-fluoro-3-{3-[2-(4-methyl-imidazol-1-yl)-thiazol-4-yl]-3-oxo-propionylamino}-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example K76) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a yellow solid (101 mg).