1-(4-Methoxyphenyl)piperazine → HCID 69605030, compound

Participants

Reaction Steps

This compound was prepared as described for Example 5, using 4-methoxyphenyl piperazine (880 mg, 4.58 mmol) and 742 mg (1.65 mmol) of [(2R)-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl 4-bromobenzene-sulfonate, to afford 560 mg (84%) of the title compound as a white solid: mp 164–165° C.; MS (ESI) m/z406 [M+H]+.

Provenance & Evidence