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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860019Generated: October 31, 2026

Phosphorus oxychloride → 2-chloro-6-(trifluoroMethoxy) quinoline

https://huagongshe.com/reaction/860019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 58765320HCID 58765320—
Product2-chloro-6-(trifluoroMethoxy) quinolineHCID 58765324—

Reaction Steps

The title compound may be prepared in a manner analogous to Example 3, Step C, from the 6-trifluoromethoxy-1H-quinolin-2-one of Step C, and phosphorous oxychloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153849B2
Source datasetuspto-grants-2006_12
ORD IDord-322ea5a0ae684df5b2a7f08ec77f8e32
Source noteuspto-grants-2006_12