Piperazine → HCID 44220318, compound

HRID 860020Notes

Reaction equation

HRID 860020 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([O:12][C:13]([F:16])([F:15])[F:14])[CH:8]=2)[N:3]=1.[NH:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[N:17]1([C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([O:12][C:13]([F:16])([F:15])[F:14])[CH:8]=3)[N:3]=2)[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 587653242-chloro-6-(trifluoroMethoxy) quinoline

Product 1

HCID 44220318HCID 44220318, compound

Procedure

The title compound is being prepared in a manner analogous to Example 3, Step D from the 2-chloro-6-trifluoromethoxy-quinoline of Step D and piperazine.

Sources & evidence

ORD record
ord-7e6fd67834f0489fbd155eefc560cec4
Source dataset
uspto-grants-2006_12
Patent number
US07153849B2

Reaction notes

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