Triethylamine → HCID 20622480, compound

HRID 860048Notes

Reaction equation

HRID 860048 reaction equation
[CH2:1]([O:5][C:6](=[O:21])[CH2:7][CH2:8][C:9]#[C:10][C:11]1[CH:12]=[CH:13][C:14]2[C:15]([N:20]=1)=[N:16][CH:17]=[CH:18][N:19]=2)[CH2:2][CH2:3][CH3:4].C(N(CC)CC)C>CCO.O=[Pt]=O.O>[CH2:1]([O:5][C:6](=[O:21])[CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][C:14]2[NH:19][CH2:18][CH2:17][NH:16][C:15]=2[N:20]=1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 2

HCID 8471TriethylamineHCID 20622479HCID 20622479, compound

Product 1

HCID 20622480HCID 20622480, compound

Reagents, catalysts & solvents 2

HCID 11139377Platinum dioxide monohydrateCatalystHCID 702EthanolSolvent

Procedure

A mixture of 5-5 (0.83 g, 2.93 mmol), triethylamine (0.222 g, 2.20 mmol), and PtO2.H2O (0.083 g) in EtOH (15 mL) was stirred under a hydrogen balloon for four hours. The reaction was filtered through Celite and concentrated to yield a dark brown oil.

Workup

  1. filtrationThe reaction was filtered through Celite
  2. concentrationconcentrated
  3. customto yield a dark brown oil

Sources & evidence

ORD record
ord-b8ac3447f2e34352bea8ff8b62c61a90
Source dataset
uspto-grants-2006_12
Patent number
US07153862B2

Reaction notes

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