Hydrochloric Acid → HCID 23435521, compound

HRID 860049Notes

Reaction equation

HRID 860049 reaction equation
C([O:5][C:6](=[O:21])[CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][C:14]2[NH:19][CH2:18][CH2:17][NH:16][C:15]=2[N:20]=1)CCC.[OH-].[Na+].Cl>CO>[NH:19]1[CH2:18][CH2:17][NH:16][C:15]2[N:20]=[C:11]([CH2:10][CH2:9][CH2:8][CH2:7][C:6]([OH:21])=[O:5])[CH:12]=[CH:13][C:14]1=2

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 20622480HCID 20622480, compound

Product 1

HCID 23435521HCID 23435521, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 5-6 (2.93 mmol) and 1.0 N NaOH solution (4.40 mL, 4.40 mmol) in MeOH (15 mL) was stirred overnight. The reaction was neutralized by adding 1.0 N HCl solution (4.40 mL, 4.40 mmol) then concentrated to yield a dark brown foam used as is in the next reaction.

Workup

  1. concentrationthen concentrated
  2. customto yield a dark brown foam
  3. customas is in the next reaction

Sources & evidence

ORD record
ord-a3c6155852364f9ab1b4ed9bd7bd652e
Source dataset
uspto-grants-2006_12
Patent number
US07153862B2

Reaction notes

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