HCID 10335523, compound → HCID 10063685, compound

Participants

Reaction Steps

The title compound, MS: m/e=306.5 (M+H+) was prepared by treatment of 100 mg 0.32 mmol) 2-chloro-6-[2-methyl-4-(2-methyl-pyridin-4-ylethynyl)-imidazol-1-yl]-pyrazine (27) with 5 equiv. of sodium methoxide in 4 ml of methanol (3 h, 55° C.). The compound, after extraction with ethyl acetate/water, was purified by chromatography. Yield: 62 mg (0.203 mmol, 63%).

Provenance & Evidence