HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57481373, compound → 7-Ethoxy-2-[(5-methyl-3-isoxazolyl)carbonyl]-7-oxoheptanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57481373 | HCID 57481373 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 7-Ethoxy-2-[(5-methyl-3-isoxazolyl)carbonyl]-7-oxoheptanoic acid | HCID 57444585 | 100% |
Reaction Steps
A solution of 1-tert-butyl 7-ethyl 2-[(5-methyl-3-isoxazolyl)carbonyl]heptanedioate (126 mg) in trifluoroacetic acid (1 mL) was stirred for 1.5 hour at room temperature. The volatile was evaporated off, and azeotroped with toluene to give 7-ethoxy-2-[(5-methyl-3-isoxazolyl)carbonyl]-7-oxoheptanoic acid as a pale orange oil (106 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153854B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-08c951ad0e55467790e9bc2a4a8d87be |
| Source note | uspto-grants-2006_12 |