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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860506Generated: November 1, 2026

HCID 68802434, compound → HCID 69309153, compound

https://huagongshe.com/reaction/860506

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68802434HCID 68802434—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 69309153HCID 6930915392.8%

Reaction Steps

A solution of 5-[7-ethyl-2-methyl-4-(2-vinyl-4-pyridinyl)pyrrolo[1,2-b]pyridazin-3-yl]pentanoic acid (15 mg) in MeOH was added 10% Pd/C (2 mg). The mixture was stirred under under hydrogen atomosphere (1 atm) for 6 h. The reaction mixture was filtered through Celite and the filtrate was concentrarted in vacuo. The residue was triturated with hexane to give 5-[7-ethyl-4-(2-ethyl-4-pyridinyl)-2-methylpyrrolo[1,2-b]pyridazin-3-yl]pentanoic acid (14 mg) as an yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153854B2
Source datasetuspto-grants-2006_12
ORD IDord-17af261910224b0eb9ca25e17970f44c
Source noteuspto-grants-2006_12