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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860674Generated: October 31, 2026

HCID 10173874, compound → HCID 58765845, compound

https://huagongshe.com/reaction/860674

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10173874HCID 10173874—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 58765845HCID 58765845—

Reaction Steps

3-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-yl]-but-3-enyloxy}-phenyl)-propionic acid (30 mg, 0.065 mmol), 10% Palladium on charcoal (30 mg) and tetrahydrofuran (30 mL) is stirred under a hydrogen balloon 30 min. The solution is filtered over celite and concentrated in vacuo to afford the title compound, 3-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-yl]-butoxy}-phenyl)-propionic acid as a white solid, 30 mg 100%. MS (M++1) 462.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153878B2
Source datasetuspto-grants-2006_12
ORD IDord-2647ec1c17d54937ae69ed7a060bcaf5
Source noteuspto-grants-2006_12