HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10173874, compound → HCID 58765845, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10173874 | HCID 10173874 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58765845 | HCID 58765845 | — |
Reaction Steps
3-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-yl]-but-3-enyloxy}-phenyl)-propionic acid (30 mg, 0.065 mmol), 10% Palladium on charcoal (30 mg) and tetrahydrofuran (30 mL) is stirred under a hydrogen balloon 30 min. The solution is filtered over celite and concentrated in vacuo to afford the title compound, 3-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-yl]-butoxy}-phenyl)-propionic acid as a white solid, 30 mg 100%. MS (M++1) 462.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153878B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-2647ec1c17d54937ae69ed7a060bcaf5 |
| Source note | uspto-grants-2006_12 |