反应详情

A solution of 4-cyanophenol (50 g), allyl bromide (27.2 ml) potassium carbonate (47.8 g) in acetone (100 ml) was heated at reflux for 16 hours. The reaction mixture was evaporated, water was added to the residue and the aqueous mixture was extracted with diethyl ether. The diethyl ether extract was washed with dilute aqueous sodium hydroxide solution, dried (MgSO4) and evaporated to give 4-cyanophenyl allyl ether as a solid, m.p. 41.6° C.; microanalysis, found: C 75.1; H, 5.8; N, 8.7%; C10H9NO2 requires: C, 75.5; H, 5.7; N, 8.8%; NMR: 4.55-4.65(2H,m), 5.2-5.4(2H,m), 5.9-6.05(1H,m), 7.0-7.1(2H,m) and 7.65-7.75(2H,m).

1. temperatureat reflux for 16 hours
2. customThe reaction mixture was evaporated
3. additionwater was added to the residue
4. extractionthe aqueous mixture was extracted with diethyl ether
5. extractionThe diethyl ether extract
6. washwas washed with dilute aqueous sodium hydroxide solution
7. dry with materialdried (MgSO4)
8. customevaporated