6-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione → 6-Amino-7-nitroquinoxaline-2,3-diol

HRID 861463Notes

Reaction equation

HRID 861463 reaction equation
FC(F)(F)C([NH:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][C:15]=1[N+:16]([O-:18])=[O:17])[NH:12][C:11](=[O:19])[C:10](=[O:20])[NH:9]2)=O>C(O)C.Cl>[NH2:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][C:15]=1[N+:16]([O-:18])=[O:17])[NH:12][C:11](=[O:19])[C:10](=[O:20])[NH:9]2

Participants

4

Reactant 1

HCID 220971576-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione

Product 1

HCID 39809926-Amino-7-nitroquinoxaline-2,3-diol

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 702EthanolSolvent

Procedure

A solution of 41 g (0.13 mol) of 6-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione in 300 ml of ethanol and 700 ml of 3 molar hydrochloric acid was refluxed for 3 hours. The reaction mixture was cooled, and the crude product was filtered off and worked up by conventional methods.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe crude product was filtered off

Sources & evidence

ORD record
ord-957ccc2a7a03478db5bdf1b5f4f781e7
Source dataset
uspto-grants-1998_02
Patent number
US05714489

Reaction notes

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