HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dimethoxytetrahydrofuran → 1-Cyclohexyl-7-nitro-6-(1-pyrrolyl)-2,3(1H,4H)-quinoxalinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dimethoxytetrahydrofuran | HCID 79098 | — |
| Reactant | 6-Amino-1-cyclohexyl-7-nitro-2,3(1H,4H)-quinoxalinedione | HCID 22097078 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Cyclohexyl-7-nitro-6-(1-pyrrolyl)-2,3(1H,4H)-quinoxalinedione | HCID 22097185 | 69% |
Reaction Steps
3.0 g (99 mmol) of 6-amino-1-cyclohexyl-7-nitro-2,3(1H,4H)-quinoxalinedione and 1.3 g (99 mmol) of 2,5-dimethoxytetrahydrofuran were refluxed in 70 ml of acetic acid for 30minutes. The mixture was then diluted with water, and the precipitate was filtered off with suction to yield 2.4 g (69%) of the product. Melting point 197° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05714489 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-dc6c0b56912347a2a473d8217c861235 |
| Source note | uspto-grants-1998_02 |