Diethyl Oxalate → HCID 22097139, compound

HRID 861509Notes

Reaction equation

HRID 861509 reaction equation
[NH2:1][C:2]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:3]=1[NH:4][CH2:5][CH:6]([CH2:9][CH3:10])[CH2:7][CH3:8].[C:16](OCC)(=[O:22])[C:17](OCC)=[O:18]>>[Cl:15][C:13]1[CH:14]=[C:2]2[C:3](=[CH:11][CH:12]=1)[N:4]([CH2:5][CH:6]([CH2:7][CH3:8])[CH2:9][CH3:10])[C:17](=[O:18])[C:16](=[O:22])[NH:1]2

Participants

3

Reactant 2

HCID 7268Diethyl OxalateHCID 22097170HCID 22097170, compound

Product 1

HCID 22097139HCID 22097139, compoundYield 76%

Procedure

35 g (0.124 mol) of 2-amino-4-chloro-N-(2-ethylbutyl)aniline were refluxed in 350 ml of diethyl oxalate for 2.5 h. After cooling, the precipitate was filtered off with suction and dried to yield 33 g (76%) of the product. Melting point 253°-255° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe precipitate was filtered off with suction
  3. customdried

Sources & evidence

ORD record
ord-e5a96a25a22942c3944dfd026392276a
Source dataset
uspto-grants-1998_02
Patent number
US05714489

Reaction notes

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