Hydrochloric Acid → HCID 19704244, compound

HRID 861548Notes

Reaction equation

HRID 861548 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]3[C:24]([S:29]([N:32]=CN(C)C)(=[O:31])=[O:30])=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:19][CH:18]=2)[C:7]2[C:13](=[O:14])[CH:12]([F:15])[CH2:11][S:10][C:8]=2[N:9]=1)[CH2:2][CH2:3][CH3:4].Cl>C(O)C>[CH2:1]([C:5]1[N:6]([CH2:16][C:17]2[CH:18]=[CH:19][C:20]([C:23]3[C:24]([S:29]([NH2:32])(=[O:30])=[O:31])=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:21][CH:22]=2)[C:7]2[C:13](=[O:14])[CH:12]([F:15])[CH2:11][S:10][C:8]=2[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86752028HCID 86752028, compound

Product 1

HCID 19704244HCID 19704244, compoundYield 96.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using the procedure of Example 2, 330 mg of the product of Example 12, 3.3 ml of ethanol and i ml of concentrated hydrochloric acid were reacted to obtain 285 mg of the crude product which was used as is in the following example and melted at 208° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-b04e1811793e43179db6fa25beff2d85
Source dataset
uspto-grants-1998_02
Patent number
US05714508

Reaction notes

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