HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tranylcypromine, cis- → (+)-N-(cis-2-phenylcyclopropyl)-N'-(5-chloropyrid-2-yl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tranylcypromine, cis- | HCID 6971118 | — |
| Reactant | N-(5-Chloropyridin-2-yl)-1H-imidazole-1-carbothioamide | HCID 10823879 | — |
| Product | (+)-N-(cis-2-phenylcyclopropyl)-N'-(5-chloropyrid-2-yl)thiourea | HCID 22868897 | — |
Reaction Steps
(-)-N-cis-2-phenylcyclopropylamine (0.23 g, 1.7 mmol) from Example 423 was condensed with 1-(5-chloropyrid-2-yl-thiocarbamoyl)-imidazole (0.4 g, 1.7 mmol) according to the procedure of Example 372 to yield the titled product as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05714503 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-5d280098060641eaa42fb6c1748f4c61 |
| Source note | uspto-grants-1998_02 |