反应详情

Arecaidine hydrochloride (4 grams) (22.6 mmoles) was hydrogenated in water (100 ml) using 10% Pd--C at 40 psi at 25° C. for 24 hours. The catalyst was filtered off and washed with water. The aqueous solution was shaken with BioRad AG1X8 resin (OH- form) (23 ml bed) and after 5 minutes the resin was filtered off and washed with water. The aqueous solution was evaporated to give the title compound (Yield: 2.95 grams, 92%).

1. customat 25° C.
2. customfor 24 hours
3. filtrationThe catalyst was filtered off
4. washwashed with water
5. filtrationwas filtered off
6. washwashed with water
7. customThe aqueous solution was evaporated