Dicyclohexylcarbodiimide → HCID 178455724, compound

Participants

Reaction Steps

1.03 g (5.00 mmol) of dicyclohexylcarbodiimide, 0.88 g (5.00 mmol) of 3,4,5-trifluorobenzoic acid and 1.02 g (5.00 mmol) of 4-(trans-4-ethylcyclohexyl)phenol are stirred at room temperature for 6 hours with 10 mg of 4-N,N-dimethylaminopyridine in 30 ml of dichloromethane. Filtration, evaporation of the solvent and purification by chromatography (silica gel/hexane) give 1.36 g of product. ##STR21## Phase sequence: X 90 (59) N (72) I

Provenance & Evidence