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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 861833Generated: October 30, 2026

Benzene → 1,1,1-trifluoro-2-phenylpropan-2-ol

https://huagongshe.com/reaction/861833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneHCID 241—
ReactantMethyl trifluoromethyl ketoneHCID 9871—
ReactantAluminum(III) ChlorideHCID 6451240—
Product1,1,1-trifluoro-2-phenylpropan-2-olHCID 123580—

Reaction Steps

1,1,1-Trifluoro-2-phenylpropan-2-ol was prepared from benzene and 1,1,1-trifluoroacetone by an AlCl3 -catalyzed Friedel-Crafts reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05716756
Source datasetuspto-grants-1998_02
ORD IDord-3c25088825e149fca836efe8b0706d00
Source noteuspto-grants-1998_02