HuagongsheHuagongshe Chemistry Print Report · For research reference only
RS 14203 → 6-(4-Pyridylmethyl)-8-(3-nitrophenyl)pyrido[2,3-d]pyridazin-5-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | RS 14203 | HCID 9808563 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-(4-Pyridylmethyl)-8-(3-nitrophenyl)pyrido[2,3-d]pyridazin-5-one hydrochloride | HCID 19700894 | — |
Reaction Steps
To a suspension of 6-(4-pyridylmethyl)-8-(3-nitrophenyl)pyrido[2,3-d]pyridazin-5-one in methanol is added 5% HCl/MeOH in a dropwise manner with stirring until a clear solution is obtained. The solvent is stripped off. The resulting solid is triturated with ethyl ether. The product is filtered off and dried under vacuum yielding 6-(4-pyridylmethyl)-8-(3-nitrophenyl)pyrido[2,3-d]pyridazin-5-one hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05716954 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-cde025d4d2fa43d495d8c216eeeae18d |
| Source note | uspto-grants-1998_02 |