Sodium Iodide → HCID 15233868, compound

HRID 861983Notes

Reaction equation

HRID 861983 reaction equation
Cl[CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[N:7]([CH:9]=[C:10]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[N:11]=2)[CH:8]=1.[Na+].[I-].[P:19]([O:26]CC)([O:23][CH2:24][CH3:25])[O:20][CH2:21][CH3:22]>>[CH2:21]([O:20][P:19]([CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[N:7]([CH:9]=[C:10]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[N:11]=2)[CH:8]=1)([O:23][CH2:24][CH3:25])=[O:26])[CH3:22]

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 31215Triethyl phosphiteHCID 15233867HCID 15233867, compound

Product 1

HCID 15233868HCID 15233868, compoundYield 43%

Procedure

By the method of Example 6, the product from Example 11 (2.66 g, 11.1 mmol) was treated with NaI (1.67 g, 11.1 mmol) and triethyl phosphite (2.03 g, 12.2 mmol). Workup produced 1.61 g (43%) of title compound.

Sources & evidence

ORD record
ord-6100a1eef5544a9c9c103d745248889c
Source dataset
uspto-grants-1998_02
Patent number
US05716964

Reaction notes

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