HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 67661237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl formate | HCID 7865 | — |
| Reactant | HCID 19701696 | HCID 19701696 | — |
| Reactant | HCID 86752044 | HCID 86752044 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67661237 | HCID 67661237 | — |
Reaction Steps
A solution of 10 g of 2-(4-methoxyphenyl)-5-methoxycarbonylmethyl-6-methylimidazolo-[2,1-b]-1,3,4-thiadiazole in 50 cm3 of methyl formate is dripped into a solution of 1.8 g of sodium hydride bromide in 10 cm3 of anhydrous dimethylformamide (DMF). The solution is left under agitation overnight at ambient temperature and is then poured into water and extracted twice with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05716974 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-c7beb16be92547e492c399c556d4cf47 |
| Source note | uspto-grants-1998_02 |