HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19701557, compound → HCID 19701629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19701557 | HCID 19701557 | — |
| Reactant | (Methanesulfinyl)methane--water (1/1) | HCID 23503278 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19701629 | HCID 19701629 | — |
Reaction Steps
By using DMSO/water (10:1), in place of DMF in Reference Example 40, 2-(5-bromo-α-cyano-4-fluoro-2-methoxymethoxybenzyl)-3-benzyloxypyridine (2.53 g) was subjected to oxidative decyanation to afford 2-(5-bromo-4-fluoro-2-methoxymethoxybenzoyl)-3-benzyloxypyridine (2.46 g) (Compound F-9). Physico-chemical properties and spectrum data are shown in Table 22 and Table 23.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05716971 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-a714cf2537784b9f8579e66b99f8d7a8 |
| Source note | uspto-grants-1998_02 |