Potassium Bromide → HCID 54463444, compound

HRID 862234Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:31])[CH2:4][N:5]1[C:10](CC2C=CC=CC=2)=[CH:9][CH:8]=[C:7]([NH:18][C:19]([O:21][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26]C=2)=[O:20])[C:6]1=[O:30].[K+].[Br-]>>[CH3:1][O:2][C:3](=[O:31])[CH2:4][N:5]1[CH:10]=[CH:9][CH:8]=[C:7]([NH:18][C:19]([O:21][CH2:22][C:23]2[CH:24]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:20])[C:6]1=[O:30]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 22104289HCID 22104289, compound

Product 1

HCID 54463444HCID 54463444, compound

Procedure

Methyl[6-benzyl-1,2-dihydro-2-oxo-3-(2-phenylethoxy)carbonylamino-1-pyridyl]acetate (49i), was isolated (88%) as a colorless solid: mp. 130°-133° C.; IR (KBr) 3363, 1746, 1732, 1651, 1604, 1515, 1368, 1231, 1212, 1185; 1H NMR (CDCl3) δ 8.00 (1H, d, J=7.0), 7.68 (1H, s), 7.36-7.10 (10H, m), 6.15 (1H, d, J=7.6), 4.7 (2H, s), 4.38 (2H, t, J=7.0), 3.88 (2H, s), 3.67 (3H, s), 2.98 (2H, t, J=7). ##STR125##

Sources & evidence

ORD record: ord-32cc2b3524ad455f92ea0c16919d15e6
Source dataset: uspto-grants-1998_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05716929

Reaction notes

Loading…