epsilon-CAPROLACTONE → Poliglecaprone

HRID 862367Notes

Reaction equation

HRID 862367 reaction equation
[CH2:1]1[O:8][C:6](=[O:7])[CH2:5][O:4][C:2]1=[O:3].[C:9]1(=[O:16])[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>>[CH2:1]1[O:8][C:6](=[O:7])[CH2:5][O:4][C:2]1=[O:3].[C:9]1(=[O:16])[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 10401epsilon-CAPROLACTONEHCID 65432Glycolide

Product 1

HCID 65431Poliglecaprone

Procedure

A process for producing a suture from a copolymer of glycolide and ε-caprolactone comprising the steps of (a) extruding a melted copolymer of glycolide and ε-caprolactone resin through an orifice and rapidly quenching the melted copolymer resin to produce a filament; (b) drawing the filament in the range of from about 4× to about 7.5× in a first drawing zone to produce a drawn filament; (c) drawing the singly drawn filament in a second drawing zone in the range of from about 1× to about 4× while in a first heated zone being maintained at a temperature in the range of from about 150° F. to about 450° F., to form a doubly drawn filament; (d) relaxing the doubly drawn filament in the range of from about 0.75× to about 0.98×, in a second heated zone being maintained at a temperature in the range of from about 100° F. to about 400° F., to form a relaxed filament; then rack annealing the relaxed filament to form a glycolide/ε-caprolactone suture.

Workup

  1. customrapidly quenching the melted copolymer resin
  2. customto produce a filament
  3. customto produce a drawn filament
  4. temperaturebeing maintained at a temperature in the range of from about 150° F. to about 450° F.
  5. customto form a doubly drawn filament
  6. temperaturein a second heated zone being maintained at a temperature in the range of from about 100° F. to about 400° F.
  7. customto form a relaxed filament

Sources & evidence

ORD record
ord-c5c9a2428c554980ac1b521b83eafa27
Source dataset
uspto-grants-1998_02
Patent number
US05718716

Reaction notes

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