epsilon-CAPROLACTONE → Poliglecaprone

Participants

Reaction Steps

A suture made from a copolymer of glycolide and ε-caprolactone made by (a) extruding a melted copolymer of glycolide and ε-caprolactone resin through an orifice and rapidly quenching the melted copolymer resin to produce a filament; (b) drawing the filament in the range of from about 4× to about 7.5× in a first drawing zone, to produce a drawn filament; (c) drawing the drawn filament in a second drawing zone in the range of from about 1.0× to about 4× while in a first heated zone being maintained at a temperature in the range of from about 150° F. to about 450° F., to form a doubly drawn filament; (d) relaxing the doubly drawn filament in the range of from about 0.75× to about 0.98×, in a second heated zone being maintained at a temperature in the range of from about 100° F. to about 400° F., to form a relaxed filament; then rack annealing the relaxed filament at a temperature of from about 85° C. to about 125° C. for at least 4 to 8 hours to form a glycolide/ε-caprolactone suture.

Provenance & Evidence