Potassium Cation → 2-Bromo-5-[({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}methyl)oxy]pyridine

HRID 86252Notes

Reaction equation

HRID 86252 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:8])[cH:6][n:7]1.[C:29](=[O:30])([O-:31])[O-:32].[CH3:9][S:10]([O:11][CH2:14][CH:15]1[CH2:16][CH2:17][N:18]([c:21]2[n:22][c:23]([CH:26]([CH3:27])[CH3:28])[n:24][o:25]2)[CH2:19][CH2:20]1)(=[O:12])=[O:13].[K+:33].[K+:34].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39].[OH2:40]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH2:14][CH:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][c:23]([CH:26]([CH3:27])[CH3:28])[n:24][o:25]3)[CH2:19][CH2:20]2)[cH:6][n:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 27628652-Bromo-5-hydroxypyridineHCID 57930198(1-(3-Isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)methyl methanesulfonate

Product 1

HCID 866387382-Bromo-5-[({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}methyl)oxy]pyridine

Sources & evidence

ORD record
ord-b8f491b934c44b38b5494554f45e8dd7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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