Methanesulfonyl chloride → HCID 67595997, compound

HRID 862532Notes

Reaction equation

HRID 862532 reaction equation
Cl.[NH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[C:11]([CH:13]([OH:21])[CH2:14][O:15][CH2:16][CH2:17][N:18]([CH3:20])[CH3:19])=[CH:10][CH:9]=[CH:8]2.[CH3:22][S:23]([Cl:26])(=[O:25])=[O:24]>C(N(CC)CC)C>[ClH:26].[CH3:20][N:18]([CH2:17][CH2:16][O:15][CH2:14][CH:13]([C:11]1[C:12]2[C:7](=[CH:6][CH:5]=[CH:4][C:3]=2[NH:2][S:23]([CH3:22])(=[O:25])=[O:24])[CH:8]=[CH:9][CH:10]=1)[OH:21])[CH3:19]

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 67597779HCID 67597779, compound

Product 1

HCID 67595997HCID 67595997, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Triethylamine was added to 1-(8-amino-1-naphthyl)-2-[2-(N,N-dimethylamino)ethoxy]ethanol hydrochloride. The resulting mixture was reacted with methanesulfonyl chloride to obtain oily 2-[2-(N,N-dimethylamino)ethoxy]-1-(8-methylsulfonylamino-1-naphthyl)ethanol hydrochloride (compound No. 291).

Sources & evidence

ORD record
ord-5e868e8c8b6743b4b3c64896cc56e6c2
Source dataset
uspto-grants-1998_02
Patent number
US05719150

Reaction notes

Loading…