Hydrochloric Acid → HCID 131720485, compound

Participants

Reaction Steps

To a solution of (S)-9-Bromo-5-[p-tert-butoxycarbonylaminomethyl-o-(3-carboxypropyl) phenylcarbamoylmethyl]-6,7-dihydro-1H, 5H-pyrido[1,2,3-de]quinoxaline-2,3-dione (103 mg, 0.164 mmol)in 1,4-dioxane (5 mL) was added 4N hydrogen chloride in 1,4-dioxane (5 mL) at room temperature. The mixture was stirred for 20 h at room temperature and concentrated. The residual solid was dried in vacuo to give 90 mg of the title compound (97%).

Provenance & Evidence