Chloroform → HCID 2797868, compound

HRID 862606Notes

Reaction equation

HRID 862606 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH:7](O)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:3][CH:2]=1.C(Cl)(Cl)[Cl:16].O=S(Cl)[Cl:21]>C(Cl)Cl>[ClH:16].[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([Cl:21])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 6212ChloroformHCID 24386Thionyl ChlorideHCID 98305α-Phenyl-4-pyridinemethanol

Product 1

HCID 2797868HCID 2797868, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 27.75 g (0.15 mol) of (4-pyridyl)benzyl alcohol and 200 ml of chloroform is run in dropwise, at room temperature, a solution of 15.25 ml (0.2 mol) of SOCl2 and 50 ml of CH2Cl2.

Workup

  1. customat room temperature

Sources & evidence

ORD record
ord-d10fc50f700d493ab1ed685d939c5f84
Source dataset
uspto-grants-1998_02
Patent number
US05719168

Reaction notes

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