HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → N-(2-pyridylmethyl)benzhydrylsulphinylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 2-Pyridinemethanamine | HCID 19509 | — |
| Reactant | Modafinil acid | HCID 3085267 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2-pyridylmethyl)benzhydrylsulphinylacetamide | HCID 15225687 | — |
Reaction Steps
To a suspension of 15.44 g (0.06 mol) of benzhydrylsulphinylacetic acid in 90 ml of methylene chloride are added 6.48 g (0.06 mol, i.e. 6.17 ml) of 2-aminomethylpyridine and 12.36 g (0.06 mol) of dicyclohexylcarbodiimide are added to the solution thus obtained. The mixture is heated at reflux for about 3 to 4 hours, then left to cool.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05719168 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-6769afe3f93e45529751b5d6b490635d |
| Source note | uspto-grants-1998_02 |